Thimerosal immuunsysteem

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De strijd tegen kwik en het effect op onze gezondheid

After decades of successfully trumpeting major environmental causes, Robert Kennedy Jr. has recently turned his attention to mercury, and its impact on human health. With major medical organizations like the Endocrine Society now recognizing toxicity as causing disease in human beings, The World Mercury Project is a timely contribution to our collective well-being. Mr. Kennedy's project is as important as it is controversial, with his focus shifting to a tenuous source of mercury in adults and humans: the modern vaccine schedule.

Thimerosal in multi-dose vaccines

This is a must see video recorded on Wednesday November 4, 2009, wherein Dr. Nicole Lurie of the Dept. of Health & Human Services admits at the end that her agency and presumably the CDC asked the vaccine makers to "expedite" making vaccines, at the risk of putting Thimerosal in the vaccines.

Rol leeftijd en gezondheid bij giftigheid Thimerosal

Affidavit Of Boyd E. Haley. Professor And Chair. Department Of Chemistry. University Of Kentucky

The detrimental effect of any specific level of mercury or mercury containing compound would have on any one individual’s metabolic system would be directly proportional to both the level of’ protective big compounds” (e.g., glutathione, metallothioine) that exist within that person on the time of exposure and, the ability to physiologically clear such toxicants from the body. The level of the protective compounds would certainly be directly dependent on two factors, age and health. Infants, with their immature physiology and metabolism would not be expected to handle mercury as efficiently as mature adults. The elderly have been shown to have decreased “protective” glutathione levels compared to middle aged and young adults. Melatonin, a hormone, is known to be decreased in the aged and melatonin is known to increase the neuron and cellular concentration of glutathione. Glutathione is the natural compound that binds mercuric ion and aids in its removal from the body. This explains partly why the aged are also more susceptible to oxidative toxicants such as mercury. The elderly also have weakened immune systems and are more susceptible to microbial infections are known to lower their chemical energy levels and, further, to reduce their ability to synthesize the proteins that protect them from heavy metals. Infants have their own weaknesses regarding toxic exposures. Infants do not make much bile in their early months of life and are less able to remove mercury through bilary transport the major route for mercury removal.



Volgens Osterhaus, Klink en Coutinho is thimerosal dus ongevaarlijk voor kids en ouderen....

De gevaren van thimerosal

Dr Boyd Haley is een hoogleraar en voorzitter van de afdeling chemie aan de Universiteit van Kentucky. Dr Haley bespreekt in dit interview, kwik toxiciteit als een causale factor bij autisme. Hij bespreekt ook de twee belangrijkste bronnen van kwik toxiciteit: vaccins & amalgaamvullingen.

Wie zit er nu te liegen ?

De Gezondheids(pharma)raad, Klink, Pinokkio Coutinho Coutinho of weblogs ? De experts zeggen dat er geen enkel bewijs is voor schadelijkheid van vaccins en thimerosal.  En deze studies dan ?

Geier, "Mitochondrial dysfunction, impaired oxidative-reduction activity, degeneration, and death in human neuronal and fetal cells induced by low-level exposure to thimerosal and other metal compounds", Toxicological & Environmental Chemistry, Volume 91, Issue 4 June 2009 5 ? 749

"The comparative toxicology of ethyl and methyl mercury" by Magos, Brown, Sparrow, Bailey, et al published in the Archives of Toxicology (1985) 57: 260-267 David S. Baskin

"Toxicity of Thimerosal", Toxicological Sciences, 2003 74 : 361-368Drs. Fagan, Pritchard, Clarkson and Greenwood "Organ mercury levels in infants with omphaloceles treated with organic mercurial antiseptic" Arch Dis Child. 1977 Dec;52(12):962-4.Dr. Mukhtarova,

"Late After-Effects Of The Nervous System Pathology Provoked By The Action Of Low Ethyl-Mercuric-Chloride Concentrations" Gig Tr Prof Zabol 1977 Mar;(3):4-7James SJ, Slikker W III, Melnyk S, New E, Pogribna M, Jernigan S (2005).

"Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors". Neurotoxicology 26 (1): 1'8. doi:10.1016/j.neuro.2004.07.012. PMID 15527868.
Baskin DS, Ngo H, Didenko VV (2003).

"Thimerosal induces DNA breaks, caspase-3 activation, membrane damage, and cell death in cultured human neurons and fibroblasts". Toxicol Sci 74 (2): 361'8. doi:10.1093/toxsci/kfg126. PMID 12773768. Ueha-Ishibashi T, Oyama Y, Nakao H et al.

De Simpsonwood-transcripties: bewijs dat de industrie weet hoe schadelijk Thimerosal is!

Het Amerikaanse congress verplichtte het FDA en andere gezondsheidsorganisaties middels
de FDA modernization act van 1997 aan te geven hoeveel zware metalen er in de diverse
farmaceutische stoffen aanwezig zijn. Het FDA en het CDC waren daardoor genoodzaakt
onderzoek te verrichten naar de giftigheid van Thimerosal / Thiomersal.


Thimerosal Ethylmercury, Vaccines and Autism

Video highlights from a two-day conference held on September 24-25, 2008 at the University of South Florida in Tampa, Florida. The "Task Force on Autism Spectrum Disorders" was created by Governor Charlie Crist by Executive Order 08-36 on March 7, 2008.

UC Davis Study with Mice Links Thimerosal with Immune System Dysfunction

A team of cell biologists, toxicologists and molecular bioscientists at the University of California, Davis, has published a study connecting thimerosal with disruptions in antigen-presenting cells known as dendritic cells obtained from mice. The study provides the first evidence that dendritic cells show unprecedented sensitivity to thimerosal, resulting in fundamental changes in the immune system's ability to respond to external factors. The study was published online today and will be available in the July print edition of Environmental Health Perspectives, the peer-reviewed scientific publication of the National Institute of Environmental Health Sciences.

"This is the first time that thimerosal has been shown to selectively alter the normal functions of dendritic cells," said Isaac Pessah, a toxicologist with the UC Davis School of Veterinary Medicine, director of the Children's Center for Environmental Health and Disease Prevention and senior author of the study. "Dendritic cells play pivotal roles in overcoming viral and bacterial invaders by coordinating the immune system's overall combat response." One dendritic cell can activate as many as 300 T-cells -- white blood cells that help find and kill external agents that attack the immune system -- making them the most effective immune system activators.

The study shows how intricate connections between calcium channels in dendritic cells change when exposed to thimerosal. "The slightest fluctuation in how calcium channels 'communicate' can alter the growth, maturation and activation of dendritic cells," explained Pessah. "Thimerosal dramatically alters how two key calcium channels, code-named RyR1 and IP3R1, found in dendritic cells function as a team by 'garbling' the normal signaling system between them."

When thimerosal at a concentration as low as 20 parts per billion alters the fidelity of normal calcium signals, dendritic cells show abnormal secretion of IL-6 cytokine -- a potent chemical signal that initiates inflammatory responses. Higher concentrations -- 200 parts per billion -- causes programmed death of dendritic cells, preventing them from maturing and doing their primary job of activating T-cells. Without proper feedback to guide its response, a normal dendritic cell can quickly become "a rogue, producing misinformation that could activate aberrant and harmful immune responses," Pessah explained. "Even one rogue dendritic cell can activate many inappropriate immune responses."

The research team conducted the study on cells cultured from a strain of mouse not particularly susceptible to immune dysregulation. Using fluorescent stains and powerful microscopes to study both immature and mature dendritic cells from bone marrow cultured under normal physiological conditions, the researchers discovered that extremely small levels of thimerosal interfere significantly with calcium channel function after just a few minutes of exposure. They also observed that immature dendritic cells are particularly sensitive to thimerosal.

Thimerosal is a cheap and effective mercury-based preservative. Its potential effects on embryonic neuron development led to its removal from many pediatric vaccines, however it is still used in influenza, diphtheria and tetanus vaccines, blood products and many over-the-counter pharmaceuticals. The concentrations of thimerosal used by the UC Davis researchers were comparable to those attained in childhood vaccinations containing the preservative.

Researchers and parents have previously proposed links between childhood vaccines and autism, a neurodevelopmental disorder that affects language skills and social interactions. In addition to being a direct neurotoxicant, the UC Davis study indicates that thimerosal may also be an immunotoxicant, leaving the immune system vulnerable to microbes and other external influences.

"Our findings do not directly implicate thimerosal as a single causative agent for triggering neurodevelopmental disorders such as autism," Pessah said. "There is growing evidence that autism is several disorders that we now refer to as just one. There is also growing evidence that some children with autism have unique immune cell composition and responses to antigens. The results of our work provide a framework to test the hypothesis that the genetic background of some individuals may render them especially susceptible to thimerosal."

Other experts also advise drawing no final conclusions regarding thimerosal and autism based on these outcomes.

"These findings should be interpreted cautiously. Although they suggest that thimerosal may affect dendritic cell function, the pathophysiological consequences of thimerosal remain unclear," said David A. Schwartz, a physician and director of the National Institute of Environmental Health Sciences.

Since cell functions can differ across organisms, Pessah will next study dendritic cells isolated from the blood of children with and without autism to confirm if the intercellular changes are the same in humans. The initial mouse study was funded by the National Institute of Environmental Health Sciences and the UC Davis M.I.N.D. Institute. Joining Pessah on the scientific team were molecular bioscientists Samuel R. Goth, Ruth A. Chu and Gennady Cherednichenko and pathologist Jeffrey P. Gregg.

A copy of "Uncoupling of ATP-mediated Calcium Signaling and Dysregulated IL-6 Secretion in Dendritic Cells by Nanomolar Thimerosal" can be downloaded at

Does the influenza vaccine contain thimerosal?

Yes, the majority of influenza vaccines distributed in the United States currently contain thimerosal as a preservative. However, some contain only trace amounts of thimerosal and are considered by the Food and Drug Administration (FDA) to be preservative-free. Manufacturers of preservative-free flu vaccine use thimerosal early in the manufacturing process. The thimerosal gets diluted as the vaccine goes through the steps in processing. By the end of the manufacturing process there is not enough thimerosal left in the vaccine to act as a preservative and the vaccine is labeled "preservative-free".


Mercury in Vaccines [ Thimerosal contains 49.6% mercury by weight]- Neuron Degeneration

At high exposure levels, mercury causes neurotoxicity in humans, especially in fetuses and small infants whose brains are still developing. The major toxicity of mercury is manifested in the central nervous system. Forty years ago, when women at Minamata Bay, Japan, ate fish contaminated with methylmercury from pollutants, their children were exposed to high levels in utero and were born with developmental and neurologic disorders. Methylmercury poisoning also occurred in Iraq following consumption of seed grain that had been treated with a fungicide containing methylmercury. In both the Japanese and Iraqi episodes, exposures to methylmercury were high

Connection between infant exposure to thimerosal-containing vaccines and neurodevelopmental injury.

I was asked to write a paper on some of the newer mechanisms of vaccine damage to the nervous system, but in the interim I came across an incredible document that should blow the lid off the cover-up being engineered by the pharmaceutical companies in conjunction with powerful governmental agencies. It all started when a friend of mind sent me a copy of a letter from Congressman David Weldon, M.D. to the director of the CDC, Dr Julie L. Gerberding, in which he alludes to a study by a Doctor Thomas Verstraeten, then representing the CDC, on the connection between infant exposure to thimerosal-containing
vaccines and neurodevelopmental injury. In this shocking letter Congressman Weldon referrers to Dr. Verstraeten's study which looked at the data from the Vaccine Safety Datalink and found a significant correlation between thimerosal exposure via vaccines and several neurodevelopmental disorders including tics, speech and language delays, and possibly to ADD.

Russell L. Blaylock,board certified neurosurgeon

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Vaccines and Childhood Illnesses: Beyond Thimerosal. David Ayoub, MD

Presentation by David Ayoub, M.D., a radiologist from Springfield, Illinois. From the 65th Annual Meeting of the Association of American Physicians and Surgeons, September 12, 2008.


Conflicts of interest in CDC Thimerosal study of 2004

Dr. Thompson – former employee of Merck;

Dr. Marcy, receiving consulting fees from Merck, Sanofi Pasteur, GlaxoSmithKline, and MedImmune;

Dr. Jackson, receiving grant support from Wyeth, Sanofi Pasteur, GlaxoSmithKline, and Novartis, lecture fees from Sanofi Pasteur, and consulting fees from Wyeth and Abbott and serving as a consultant to the FDA Vaccines and Related Biological Products Advisory Committee;

Dr. Lieu, serving as a consultant to the CDC Advisory Committee on Immunization Practices;

Dr. Black, receiving consulting fees from MedImmune, GlaxoSmithKline, Novartis, and Merck and grant support from MedImmune, GlaxoSmithKline, Aventis, Merck, and Novartis;

and Dr. Davis receiving consulting fees from Merck and grant support from Merck and GlaxoSmithKline.


Thimerosal in Childhood Vaccines, Neurodevelopment Disorders, and Heart Disease in the United States

This study provides strong epidemiological evidence for a link between increasing mercury from thimerosalcontaining childhood vaccines and neurodevelopment disorders and heart disease. In light of voluminous literature supporting the biologic mechanisms for mercury-induced adverse reactions, the presence of amounts of mercury in thimerosal-containing childhood vaccines exceeding Federal Safety Guidelines for
the oral ingestion of mercury, and previous epidemiological studies showing adverse reactions from such vaccines, a causal relationship between thimerosalcontaining childhood vaccines and neurodevelopment disorders and heartdisease appears to be confirmed. It is to be hoped that complete removal of thimerosal from all childhood vaccines will help to stem the tragic, apparently iatrogenic epidemic of autism and speech disorders that the United States is now facing.

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Is There a Connection with Vaccines and Autism?

Why are so many children in the U.S. diagnosed with some form of Autism Spectrum Disorder? Is there a connection between Vaccines and Autism? In this program, two nationally recognized journalists will debate this topic. Join Arthur Allen, author of Vaccine: The Controversial Story of Medicine's Greatest Lifesaver and David Kirby author of Evidence of Harm, as they present both sides of this debate.

Thimerosal, Methylmercury React Differently in the Brains of Infants, Study Says Report in Environmental Health Perspectives finds methylmercury not a suitable reference for risk assessment

Researchers have uncovered greater detail about differences in how thimerosalÑa preservative used in vaccines since the 1930s-and methylmercury are distributed in and eliminated from the brain and body, as reported in a study published online today by the peer-reviewed journal Environmental Health Perspectives. Among other effects, researchers found that brain concentrations of total mercury following thimerosal exposure were nearly threefold lower than those following methylmercury exposure. These findings are important because they demonstrate that methylmercury is not a suitable reference for determining risk from exposure to thimerosal. The current debate over a potential link between thimerosal in vaccines and autism has led many families to question whether the risk of developing the disorder is greater than the benefit of vaccination.

Thimerosal breaks down in the body to ethylmercury and thiosalicylate. Because few health effects data exist for ethylmercury, methylmercury guidelines have been used to predict the toxicokinetics and neurodevelopmental effects of ethylmercury exposure. An earlier study calculated that children receive 187.5 micrograms of ethylmercury from thimerosal-containing vaccines given over the first 14 weeks of life, which can exceed EPA guidelines for methylmercury exposure during pregnancy.

In the present study, researchers exposed 41 infant Macaca fascicularis, or crab-eating monkeys, to thimerosal and methylmercury. These monkeys are among the best proxies for infant humans. Infants assigned to the thimerosal group received the typical schedule of injected vaccines for human infants, while infants assigned to the methylmercury group were exposed through a feeding tube.

Absorption and initial distribution of total mercury proved to be similar for both thimerosal and methylmercury. However, injected thimerosal reacted differently from methylmercury in that it cleared from the infant much more quickly. Also the peak blood mercury concentration in the methylmercury group rose to a level three times higher than the thimerosal infants after the fourth dose. Brain concentrations of total mercury were significantly lower for the thimerosal group compared to the methylmercury group.

These results suggest that ethylmercury is dealkylated much more extensively than methylmercury. While dealkylation is thought to be a detoxification mechanism that helps protect the central nervous system, previous work by Burbacher and his group has shown that inorganic mercury can affect certain types of cells in the brain such as the microglia. Recent reports have indicated abnormal microglia in the brains of children with autism.

According to the researchers, more research is needed to accurately predict how immunization with thimerosal-containing vaccines may affect children. "Knowledge of the biotransformation of thimerosal . . . is urgently needed to afford a meaningful interpretation of the potential developmental effects of immunization with thimerosal-containing vaccines in newborns and infants," the study authors write. "This information is critical if we are to respond to public concerns regarding the safety of childhood immunizations."

Dr. Jim Burkhart, science editor for EHP, says, "This study emphasizes that thimerosal and methylmercury behave differently in the body. Given that we routinely inject thimerosal into millions of infants, the study authors' call for more in-depth research on the subject is the right way to go."

The lead author of the study was Thomas M. Burbacher of the University of Washington. Other authors included Danny D. Shen, Noelle Liberato, Kimberly S. Grant, Elsa Cernichiari, and Thomas Clarkson. The study was funded by the National Institute of Environmental Health Sciences, the National Institute of Allergy and Infectious Diseases, the National Institute of Child Health and Human Development, the National Center for Research Resources, and the University of Rochester. The article is available free of charge at, and will be published in an upcoming print edition of the journal.

Robert Kennedy on the Vaccine Autism Coverup

According to a CDC epidemiologist named Tom Verstraeten, who had analyzed the agency's massive database containing the medical records of 100,000 children, a mercury-based preservative in the vaccines -- thimerosal -- appeared to be responsible for a dramatic increase in autism and a host of other neurological disorders among children. "I was actually stunned by what I saw," Verstraeten told those assembled at Simpsonwood, citing the staggering number of earlier studies that indicate a link between thimerosal and speech delays, attention-deficit disorder, hyperactivity and autism. Since 1991, when the CDC and the FDA had recommended that three additional vaccines laced with the preservative be given to extremely young infants -- in one case, within hours of birth -- the estimated number of cases of autism had increased fifteenfold, from one in every 2,500 children to one in 166 children.

Comparison of Blood and Brain Mercury Levels in Infant Monkeys Exposed to Methylmercury or Vaccines Containing Thimerosal

Thimerosal is a preservative that has been used in manufacturing vaccines since the 1930s. Reports have indicated that infants can receive ethylmercury (in the form of thimerosal) at or above the U.S. Environmental Protection Agency guidelines for methylmercury exposure, depending on the exact vaccinations, schedule, and size of the infant. In this study we compared the systemic disposition and brain distribution of total and inorganic mercury in infant monkeys after thimerosal exposure with those exposed to MeHg. Monkeys were exposed to MeHg (via oral gavage) or vaccines containing thimerosal (via intramuscular injection) at birth and 1, 2, and 3 weeks of age. Total blood Hg levels were determined 2, 4, and 7 days after each exposure. Total and inorganic brain Hg levels were assessed 2, 4, 7, or 28 days after the last exposure. The initial and terminal half-life of Hg in blood after thimerosal exposure was 2.1 and 8.6 days, respectively, which are significantly shorter than the elimination half-life of Hg after MeHg exposure at 21.5 days. Brain concentrations of total Hg were significantly lower by approximately 3-fold for the thimerosal-exposed monkeys when compared with the MeHg infants, whereas the average brain-to-blood concentration ratio was slightly higher for the thimerosal-exposed monkeys (3.5 ± 0.5 vs. 2.5 ± 0.3) . A higher percentage of the total Hg in the brain was in the form of inorganic Hg for the thimerosal-exposed monkeys (34% vs. 7%) . The results indicate that MeHg is not a suitable reference for risk assessment from exposure to thimerosal-derived Hg. Knowledge of the toxicokinetics and developmental toxicity of thimerosal is needed to afford a meaningful assessment of the developmental effects of thimerosal-containing vaccines. Key words: brain and blood distribution, elimination half-life, ethylmercury, infant nonhuman primates, methylmercury, thimerosal. Environ Health Perspect 113: 1015-1021 (2005) .

Autism link with vaccines - Dr. Andrew Wakefield

Anti-Anti-Vax Steve Novella

The Amaz!ng Meeting 7 Panel discussion about the Anti Vax movement. The benefits of vaccination far outweigh the supposed risks. The panel talk gave many examples of how vaccines have helped eradicate diseases that caused millions of deaths around the world. Steve Novella an American clinical neurologist, assistant professor and Director of General Neurology at Yale University School of Medicine. Novella is best known for his involvement in the skeptical movement.
Full Panel Discussion video is available on the TAM 7 DVD set at




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